Thermal analysis: characterization, instrumentation, simulation

We characterize and model heat transfer to help you improve your materials, products and manufacturing processes.

Measuring and simulating heat transfers to improve the thermal performance of your product or process is the heart of our expertise. Thanks to tests, analyzes and simulation performed at the level of the constituent, the material or the final product, we guide you in your choices and in the optimization of your forming processes.

Depending on the requirements of your projects or issues, our experts can characterize your products, design original test benches, imagine tailor-made instrumentation campaigns in the laboratory or on site and develop specific simulation tools.

Summary

Advanced thermal characterization of materials

Equipped with a wide range of thermal characterization devices, either commercial instruments or specifically developed experimental benches, our engineers take care to characterize the thermal properties of your solid and liquid materials under the closest conditions of your process, according to actual conditions of manufacture and use of your products.

In a nutshell

Conduction

Calorimetry

Volume evolution

Radiative properties

rheology – degradation

Conduction

Calorimetry

Volume evolution

Radiative properties

Rheology and degradation

Modelling, Thermal simulation

We offer solutions for modeling heat transfer on processes, taking into account possible couplings with other physics. Our modeling expertise, combined with our thermal experience, allows to size, understand, or even optimize your industrial processes.

In a nutshell

Comparative studies

Design assistance

Thermal phenomena

Prediction of defects

Thermal optimization

Sizing and design assistance

Understand thermal phenomena

Optimization

Development of integrated metrology solutions

We develop personalized metrology solutions, ranging from on-site thermal instrumentation, to the development of specific sensors or protocols, to the design of original experimental benches. Based on our experience in thermal metrology, we strive to carry out measurements under conditions closest to the actual process, while installing the least intrusive sensors.

In a nutshell

Thermal instrumentation

specific sensors

experimental benches

sizing and instrumentation

Thermal instrumentation

Development of specific sensors and protocols

Design of original experimental benches

Composite forming : thermal analysis of processes

From the advanced characterisation of your composite materials to the optimisation of the thermal parameters of your forming processes, we bring to your R&D projects our advanced scientific expertise.

In a nutshell

Conductivity

Thermal expansion

Rheology

Radiative properties

Welding thermoplastic composites

simulation

Laboratoire LTEN
Comsol

Engineering at CAPACITÉS

Our research laboratories

Our materials experts carry out their engineering work directly in the research laboratories of  Nantes Université, notably at LTeN. On a daily basis, they combine technical resources and scientific discoveries to meet your R&D challenges.

Certified Consultant

As certified consultants with COMSOL Multiphysics, we use our experience with this software to provide solutions for a wide range of thermal simulation projects.

Challenges we’ve met

Need an innovative and resourceful partner?

Capacités teams inspire, harness and couple numerous cutting-edge skills covering a wide range of applications and expertise to meet all of your innovation needs with passion and commitment!

or send us a message:






    Required fields

    Analytical chemistry : NMR, 2D NMR, IRMS

    Our experts in analytical chemistry provide your projects with exceptional technical resources and know-how.

    Our Capacités experts in analytical chemistry have developed an exceptional know-how in Nuclear Magnetic Resonance (1D NMR and 2D NMR) and in Isotope Ratio Mass Spectrometry (IRMS).
    Access to a large pool of equipment allows us to support industrial projects, from sample preparation to characterization.

    We are specialized in very high precision quantification projects and in the analysis of complex matrices. We help our clients to innovate in the study of metabolism, the fight against counterfeiting, the determination of the purity of active molecules, or the monitoring of chemical transformations.

    Summary

    Services

    Strategy and consulting

    Diagnosis and selection

    Process development

    Quality control

    Development of methods

    Metabolomic and lipidomic analyses

    Validate a therapeutic target or refine the description of a pathology through the identification and qualification of biomarkers responsible for changes between two states.

    Our experts master different types of analyses of biological samples. They perform targeted and non-targeted profiling and highlight changes between states of the biological matrices studied.

    In a nutshell

    Targeted analysis

    Metabolomic profiling

    Metabolic Footprint

    Analysis of matrices

    Data processing

    Targeted analysis

    Metabolomic profiling

    Metabolic Footprint

    Analysis of matrices

    Data processing

    Quantitative NMR (nuclear magnetic resonance)

    Our expertise is to qualify reference substances, determine the purity of molecules and certify their compliance with international quality standards.

    Our experts assist pharmaceutical and cosmetic companies in certifying the purity of their reference molecules using NMR methods.

    In a nutshell

    NMR acquisition parameters

    NMR processing parameters

    Method validation and parameter verification

    Product origin authentification

    Optimization of the NMR tool

    NMR acquisition parameters

    NMR processing parameters

    Method validation and parameter verification

    Product origin authentification

    Optimization of the NMR tool

    Publication

    Didier G. Diomande, Estelle Martineau, Alexis Gilbert, Pierrick Nun, Ariaki Murata, Keita Yamada, Naoharu Watanabe, Illa Tea, Richard J. Robins, Naohiro Yoshida, and Gérald S. Remaud Position-Specific Isotope Analysis of Xanthines: A 13C Nuclear Magnetic Resonance Method to Determine the 13C Intramolecular Composition at Natural Abundance.v

    Analytical Chemistry 2015 87 (13), 6600-6606. DOI: 10.1021/acs.analchem.5b00559

    Quantitative 2D NMR (2D nuclear magnetic resonance)

    Development of fast and quantitative 2D NMR acquisition methods.

    Our experts have developed a protocol for the implementation of targeted and non-targeted metabolic and lipidomic studies.

    In a nutshell

    Rapid quantification for metabolomics and lipidomics

    Quantification of polysaccharides by 2D NMR

    Rapid quantification for metabolomics and lipidomics

    Quantification of polysaccharides by 2D NMR

    Publication

    Estelle Martineau, Serge Akoka, Renaud Boisseau, Benoît Delanoue, and Patrick Giraudeau. Fast Quantitative 1H–13C Two-Dimensional NMR with Very High PrecisionAnalytical Chemistry 2013 85 (9), 4777-4783

    Estelle Martineau, Kamel El Khantache, Marion Pupier, Patricia Sepulcri, Serge Akoka, Patrick Giraudeau, Non-linear effects in quantitative 2D NMR of polysaccharides: Pitfalls and how to avoid them, Journal of Pharmaceutical and Biomedical Analysis, Volume 108, 2015, Pages 78-85, ISSN 0731-7085

    Estelle Martineau, Jean-Nicolas Dumez, Patrick Giraudeau. Fast quantitative 2D NMR for metabolomics and lipidomics: A tutorial Magnetic Resonance in Chemistry. 04 June 2019

    IRMS (Isotope Ratio Mass Spectrometry)

    To analyze the 13C, 15N, 2H, 18O and 34S isotopes present in organic matter, for a better understanding of metabolism in the fields of health and nutrition.

    The mastery of compound-specific analysis allows to obtain 13C and/or 15N profiles of different matrices.

    In a nutshell

    Average isotopic composition by EA-IRMS

    GC-IRMS analyse

    Average isotopic composition by EA-IRMS

    GC-IRMS analyse

    Publication

    Tea, I., Martineau, E., Antheaume, I. et al. 13C and 15N natural isotope abundance reflects breast cancer cell metabolism. Sci Rep 6, 34251 (2016). https://doi.org/10.1038/srep34251

    Olivier L Mantha, Caroline Goupille, Jean-François Dumas, Richard Robins, Philippe Bougnoux, Régis Hankard, Arnaud De Luca, Natural isotopic abundances as markers of compliance in clinical trialsThe American Journal of Clinical Nutrition, Volume 111, Issue 5, May 2020, Pages 1109–1110

    Tea I, Le Guennec A, Frasquet-Darrieux M, Julien M, Romek K, Antheaume I, Hankard R, Robins RJ. Simultaneous determination of natural-abundance δ15N values and quantities of individual amino acids in proteins from milk of lactating women and from infant hair using gas chromatography/isotope ratio mass spectrometry. Rapid Commun Mass Spectrom. 2013 Jun 30;27(12):1345-53.

    Engineering at CAPACITÉS

    Our Analytical Chemistry experts perform their engineering duties in the very research laboratories of Nantes Université themselves, most notably at CEISAM. They strive to combine technical resources and scientific discovery to meet your R&D needs.

    Challenges we’ve met

    Need an innovative and resourceful partner?

    Capacités teams inspire, harness and couple numerous cutting-edge skills covering a wide range of applications and expertise to meet all of your innovation needs with passion and commitment!

    or send us a message:






      Required fields