Our experts in viral vector production work in the gene therapy laboratory in Nantes to support you in the development of new drugs.
CAPACITÉS’ teams in monitoring host immune response, preclinical assays and viral vector production offer a complete range of support for the development of drug candidates.
With internationally recognized know-how in the field of gene therapy, our experts offer the responsiveness of a CRO (Contract Research Organization) in the discovery and development phases of gene therapy products.
Proof of concept
In close collaboration with the UMR 1089 gene therapy laboratory (UMR INSERM-Université de Nantes), we propose the development of processes for the production and characterization of viral gene transfer vectors derived from adenoviruses and AAV. These vectors are intended for applications ranging from basic research to preclinical trials.
The research teams and the vector production center of Nantes UMR1089 gene therapy laboratory work together to ensure reliable, high-quality production and characterization of viral vectors. They can also develop custom analytical tests and new innovative characterization tests.
Experts in the monitoring of host immunity in gene therapy protocols, we provide analyses for monitoring immune responses directed against the vector and against the transgene product. We assist in the development of your gene therapy products, from the research project to toxicology studies and clinical trials.
Analyses for monitoring the immune response against the vector or the transgene product are carried out by the GTI (Gene Therapy Immunology Core) platform of the Nantes UMR1089 gene therapy laboratory. This platform has complete technical means for the Immune monitoring of gene therapy studies.
Evaluation of the biodistribution and expression profile of transgenes is necessary to understand the pharmacology and pharmacokinetics of a therapeutic product. We are recognized as experts in the molecular and biochemical analyses required to assess the efficacy and biosafety of gene therapy products.
Our leading expertise, in the evaluation of biodistribution and expression profiles of transgenes, is implemented using multiple tools and equipment available on PAC (Preclinical Analytics Core) platform of the Nantes UMR1089 gene therapy laboratory.
Our gene therapy experts carry out their engineering work directly in the research laboratories of Nantes Université, particularly in the Nantes gene therapy laboratory (UMR 1089).
On a daily basis, they combine technical resources and scientific discoveries to meet your R&D challenges.